Characteristics, Treatment Options for Patients With Advanced Gynecologic Cancers

The management of advanced gynecologic cancers remains a challenge, but the treatment landscape is changing for cervical, ovarian, and endometrial cancers. Paula Anastasia, MN, RN, AOCN, a nursing education consultant, reviewed data on gynecologic cancers and discussed the diagnosis and treatment of these malignancies in an oral presentation at the 2023 ONA Summit Live Virtual […]

Read More

Women With BRCA1/2 Mutations Have High Risk of Cancer After Age 50

(HealthDay News) — The risk of cancer remains high for women older than 50 years with BRCA1 or BRCA2 mutations, according to a study published in Cancer. Researchers estimated the cumulative risks for all cancers in women from 50 to 75 years of age with a BRCA1 or BRCA2 pathogenic variant. The analysis included 2211 women seen at 85 centers in 16 countries who […]

Read More

Frequent Aspirin Use Reduces Risk For Nonmucinous Ovarian Cancer Regardless Of Genetic Susceptibility

Healio (2/27, Welsh) reported, “Daily or near daily aspirin use reduced the risk for nonmucinous ovarian cancer across most strata of genetic risk based on a polygenic score, according to a case-control study” that “pooled individual-level data from eight population-based case-control studies.” The findings were published in JAMA Network Open. […]

Read More

Just 14% Of All Diagnosed Cancers In US Are Detected By Screening With Recommended Screening Test

CNN (12/14, Howard) reported, “A small proportion – 14.1% – of all diagnosed cancers in the United States are detected by screening with a recommended screening test, according to a new report.” Other “diagnosed cancers tend to be found when someone has symptoms or seeks imaging or medical care for other reasons, suggests the report.” The findings were posted […]

Read More

Researchers Use CRISPR To Boost Cancer Immunotherapy

HealthDay (11/10, Thompson) reported, “Gene editing has for the first time produced modified immune cells finely honed to target and attack cancer cells, researchers say.” The investigators “used…CRISPR to alter immune cells drawn from 16 patients who had a variety of solid cancers, including colon, breast and lung.” The findings were published in Nature and will be presented at […]

Read More

Insurance Types Impact Quality Of Care For Patients With Gynecologic Cancers

Targeted Oncology (10/14, Sava) reported, “Whether a patient with gynecologic cancer has insurance or is underinsured, there are major barriers which currently exist in accessing and affording quality care for the treatment of their cancer.” Such “disparities are a major problem as they contribute to one-third of women with gynecologic cancer never visiting a gynecologic oncologist, even […]

Read More

First-Line Maintenance Rucaparib Yields Higher PFS Compared With Newly Diagnosed Ovarian Cancer

Cancer Network  (9/30, Conroy) reported, “First-line maintenance rucaparib (Rubraca) yielded higher progression-free survival (PFS) compared with placebo among patients with newly diagnosed ovarian cancer regardless of cytoreductive surgery outcome and was favored across all subgroups, according to the results of the phase 3 ATHENA-MONO study.” These results were presented at the International Gynecologic Cancer Society 2022 […]

Read More

Researchers Develop Automated Liquid Biopsy Test That Can Detect Cancer DNA In Blood Of Patients With Metastatic Breast Cancer Within Five Hours

Healio (8/12, Byrne) reported researchers “have developed an automated liquid biopsy test that can detect cancer DNA in the blood of patients with metastatic breast cancer within 5 hours.” The tool dubbed “Liquid Biopsy for Breast Cancer Methylation (LBx-BCM) works with a currently available molecular testing platform, GeneXpert (Cepheid), and can detect methylation in one or […]

Read More